Researchers at Boston College and Washington University School of Medicine have found evidence that supports the theoretical origin of cancerous cells first proposed by Otto H. Warburg in 1924.The Warburg theory of cancer proposed defects in the mitochondria, the metabolic "power plant" for the cell, as the cause of mutations and cancerous growth. Scientists have now identified a cellular lipid called cardiolipin that is used by the mitochondria in its normal function. Abnormalities in the quantity or composition of cardiolipin have been correlated with all types of cancerous tumors, as well as the energy-producing capacity of the cell.
A noted German biochemist, Warburg first proposed in 1924 that the cause of cancer was mutation or injury to a cell's mitochondria, thereby leading to irreversible damage and significant reductions in cellular metabolism. Warburg's work earned him the 1931 Nobel Prize for Medicine.
These results were published in the December edition of the Journal of Lipid Research.
Source: ScienceDaily; Photo: Wikipedia
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