Researchers at the Federation of American Societies for Experimental Biology (FASEB) have discovered the reason that hair turns gray as we age.
Gray hair results from a natural build-up over time of hydrogen peroxide (H2O2) in hair follicles, essentially bleaching the hair from within. This accumulation is cause by a reduction of a certain enzyme called catalase that breaks down hydrogen peroxide into water and oxygen. Hair follicles cannot repair the damage caused by hydrogen peroxide because of low levels of other enzymes methionine sulfoxide reductase (MSR) A and B that normally serve this function.
At the same time, the high levels of hydrogen peroxide and low levels of MSR A and B also disrupt the formation of the enzyme tyrosinase, which is responsible for the production of the natural pigment melanin. Researchers also speculate that a similar process is responsible for loss of pigment in certain skin conditions such as leukoderma.
These results were published in a recent edition of the FASEB Journal.
Source: ScienceDaily
Saturday, February 28, 2009
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